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antacids increase pneumonia risk-JAMA

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antacids increase pneumonia risk-JAMA

Posted by ANN [1003.516] on November 08, 2004 at 17:29:56:

US News and World Report 11/8/04, page,74, STOMACH ACID REDUX:
Acid infdigestion, gastric reflux, ulcers, and other digestive problems plague about a third of the United States population and make for a $13 billion-a -year antacid industry. Newer acid-suppressing drugs-the H-2 receptor antagonists, such as Tagamet and Zantac, and the proton pump inhibitors, Prrilosec and Nexium- have spelled relief for millions of people.
But a study published in the Journal of the American Medical Association adds a sour note to the safety record of these stomach-sweetening drugs. Among some 364.700 Dutch patients, those taking these acid-suppressing drugs developed pneumonia 4 1/2 times more often than people who never took the drugs. The risk was greatest for people taking proton pump inhibitors [Prilosec and Nexium]. Why? Because stomach acid protects the body from invasion by pathogens through the gastrointestinal tract. Pneumonia can be deadly to the elderly, who tend to be major consumers of acid-suppressing drugs.



Re: antacids increase pneumonia risk-JAMA

Posted by Jayne [819.91] on November 08, 2004 at 19:02:53:

In Reply to: antacids increase pneumonia risk-JAMA posted by ANN [1003.516] on November 08, 2004 at 17:29:56:

ANN - am I glad you posted this!! forwarding to a friend!

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Re: antacids increase pneumonia risk-JAMA (Archive in aging.)

Posted by Walt Stoll [9.8] on November 09, 2004 at 07:49:53:

In Reply to: antacids increase pneumonia risk-JAMA posted by ANN [1003.516] on November 08, 2004 at 17:29:56:

Thanks, Ann.

Walt

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