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My 21 month old son had an allergic reaction to Amoxicillin which resulted in a sever case of serum sickness. His joint pain and fever lasted 40 days. He was treated with ibuprofen and one three day dose of prednisone. He was seemingly cured after about 50 days. I inquired to his doctor about possible complications of this illness and was told that there were no concerns. A month and a half after his final follow-up visit he went into a seizure and died. His autopsy discovered Thrombus in the pericardium around his heart. How often does this happen? Because of the similarities to JRA are children with that disorder also at risk for this condition?
In Reply to: serum sickness posted by Amy Lance on August 28, 2002 at 08:49:33:
Hi, Amy.
I am sorry to hear of your loss!
In MY opinion, I think these were related. You are going to have to read up on the long-term complications of serum sickness to find the connection and I would suggest you do so.
What was the amoxicillin given for?
Walt
In Reply to: Re: serum sickness (Archive in immunity.) posted by Walt Stoll on August 29, 2002 at 11:34:54:
Hi Dr. Stoll,
The amoxicillin was given for an ear infection. Since my initial question we have received Harrison's autopsy report and he was diagnosed as having Kawasaki's disease. This is very confusing to us because he only had three of the symptoms and they seem the same as serum sickness. His entire heart was affected. It is hard to believe that he continued to play right up to his first attack. He recovered from that spell only to die an hour and a half later. When high spiking fever persists is it common to be concerned for heart damage regardless of the cause of the fever? I am having a hard time understanding why his doctor never mentioned complications even after I asked about them. Thank you for any info you can offer me.
Sincerely,
Amy
In Reply to: Re: serum sickness (Archive in immunity.) posted by Amy Lance on September 13, 2002 at 11:22:18:
Hi, Amy.
In my opinion; Isn't it interesting that, although all research (over the past 20 years) has shown that antibiotics are of absolutely no use in middle ear infections, lazy physicians still continue to prescribe them for this preventable condition (See ears archives.)?
Once his immune system is so deeply affected, his only option is serious wellness for the rest of his life.
Let us know how he does.
Walt
In Reply to: Re: serum sickness (Archive in immunity.) posted by Walt Stoll on September 14, 2002 at 08:29:04:
Dear Walt,
I'm afraid that Harrison can't practice serious wllness because he was diagnosed with Kawasaki's disease after his death. My question in my last e-mail was about the affects of high spiking fevers on the coronary arteries. Does it matter what causes the fever or is fever itself dangerous.
Thank you,
Amy
In Reply to: Re: serum sickness (Archive in immunity.) posted by Amy Lance on September 15, 2002 at 15:09:41:
Thanks, Amy.
Chalk one more up to the "monopoly".
Since it is now known that "inflammation" is at least a major cause of atherosclerosis, I would think that fever (depending on the cause) would not be good for it.
Walt
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