A doctor has told me that I have a high uric acid level of 9.5. My understanding is that levels between 8 and 4.5 are considered normal. The doctor has recommend that I take allopurinol every day for the rest of my life. My question is, is there not an alternative to taking drugs for the rest of my life. I was 75 pounds overweight and went on a high protein diet, at that time my uric acid level was 10.5. I have taken off 20 pounds so far, and I feel good. If I take off the rest of the 55 pounds and watch what I eat, a low fat and low purine diet, will my uric acid level go down? Or am I stuck taking drugs for the rest of my life? Will oral chelation therapy remove uric acid crystal deposits in and around the joints through out the body.
In Reply to: Uric Acid and Chelation Therapy posted by Roy on February 05, 1998 at 15:43:58:
First, allopurinal is one of those serendipidous discoveries that sometimes work so much like our own processes that they cannot really be considered a "drug" like much of the rest that we know of.
Gout is a congenital condition. One is born without the ability to make the enzyme that converts uric acid to urea. Since there is widely varying "penetrance" of this genetic lack, some people cannot do it at all (those get gout as infants.) and some just are not as good at it as the "normal" people are (those may not get gout till they are 90.)
Did you get a 24 hour urine for uric acid or did you have the diagnosis just by blood? About 90% of all diagnosed gout is NOT gout and most of the erroneous diagnoses were made by the simplistic tendency of a lazy doc to make the diagnosis superficially.
Allopurinal almost perfectly duplicates the enzyme your body should be making anyhow (IF you truly have goute--there are a lot of things that will elevate blood uric acid other than goute.) and replacing that enzyme with allopurinal for the rest of your life is exactly what you should do. It is a lot like taking insulin for diabetes. your body needs it.
Since the breakdown of protein in your body inevitably leads to uric acid and then (normally) to urea, reducing the protein in your diet would help (IF your blood results are due to gout.) Would it help enough? Only trying it would tell.
However, the accumulation of uric acid in your tissues is what causes gouty symptoms. If you truly have goute, the only way for you to stop the symptoms permanently is to reduce the storage in your tissues. That means you have to excrete it faster than you make it.
Uric acid is not nearly as soluble in water as urea. Since the pathway for this stuff to get out of your body is to be dissolved in urine (urea is why urine has its name), the more soluble the molecule can be the more successful it will be excreted. If you stop with uric acid, lots of it will be deposited in your tissues.
Read the package insert for allopurinal. It is a very safe substance. If you truly have gout, you need it.
These are things your own doc should have explained to you.
In Reply to: Re: Uric Acid and Chelation Therapy posted by Walt Stoll on February 07, 1998 at 08:37:53:
Is the inability to process purines a 'defect' in the inherited enzyme system of this gentleman or is it just a presentation of his inherited metabolism -- much as the inability of some African peoples to digest milk (since they completely lack enzymes required to break down lactose)?
There are other important considerations for this gentleman even if he takes allopurinol for the rest of his life. He will always be swimming against the tide of his inherited metabolism as long as he is eating a high protein (and high purine) diet. In other words he may not have goute any more but there will be another leak that will spring in the dike shortly -- probably with some bad cholesterol figures (especially a bad HDL/LDL ratio and high risk for cardiovascular disease). Even though his diet has helped him lose weight it is not appropriate for what he has inherited metabolically speaking.
Others will find that in the same manner that this gentleman is poisoned by excessive amounts of purines that they will be poisoned by excessive amounts of carbohydrate and not enough purine.
In Reply to: Re: Uric Acid and Chelation Therapy posted by Robert McFerran on February 08, 1998 at 22:44:19:
You are absolutely right. That is why I tried to alert this person as to the fact that he needed to know a lot more than what his blood uric acid is.
I am hoping that, if his doc made the diagnosis simply by the blood level he would begin to realize he needed a more thorough doc.
I am glad you said what you said since it further opens the door to what he really needs to be thinking about.
In Reply to: Re: Uric Acid and Chelation Therapy posted by Walt Stoll on February 09, 1998 at 11:14:30:
I want to thank both of you gentlemen for your thoughts.
I would still like to know if oral chelation therapy will remove uric acid from my tissues, and will it remove the uric acid crystal deposits in and around the joints through out the body?
To answer your question, the diagnosis was just by blood.
And you are right, these are things my doctor should have explained to me. I do not know all of the correct questions to ask, and I have a hard time getting him to take the time to explain anything. I have decided to change doctors, and I have asked another doctor to check thing out.
Will keep you updated.
In Reply to: Re: Love and Anger posted by Jim on February 09, 1998 at 10:16:07:
Ornish was "dancing on the edge" 20 years ago when he reported that yoga, aerobics & a 10% fat diet would eliminate all symptoms (within a month) in 90% of all patients participating who had been told that bypass surgery was their only answer. Physicians are finally BEGINNING to catch up with that. By 10 more years they will be taking Ornish's work as their own. Perhaps 30 years from now, thsy will take THIS as their own.
Larry Dossey, MD has lectured for years (as have I) that humans are the only creatures that can decide when to have their coronaries. When do you think most coronaries take place (day of the week & time of day)? I give you one guess.
Your comments are, as usual, RIGHT ON!
In Reply to: Re: Uric Acid and Chelation Therapy posted by Roy on February 09, 1998 at 16:42:58:
So far as I know, oral chelation will not remove uric acid from your tissues. The only thing I know of is to reduce the blood uric acid enough that the tissue uric acid will diffuse from the higher concentration to the lower. It usually takes 6-12 months for the stuff to leak out.
In Reply to: Re: epstein barr virus posted by Sharon Fanucce on February 14, 1998 at 19:53:01:
What your son needs is at least 50 grams of vitamin C, intravenously, every day for about 5 days. This totally safe procedure cleared every case of acute Mono within a week--once I knew enough to use it.
You could contact Robert Cathcart, MD, at (415) 949-2822 and ask for the names of the closest physicians who would know how to do this. OR, you could call (800) 532-3688 and ask them for the closest physicians certified in chelation therapy since they would at least know how to give 50 grams of vitamin C in an IV drip.
For your son to have this bad a case, it means that his immunity has been compromized & it would behoove both of you to do something about that. The most powerful approach known is a wellness program. The only problem is that it is HE that will have to learn about it AND do it. The complete protocol (and references) are in the back of my book (link below). Nothing either of us can do or say will do it for him. You know how teenagers are! I have raised 4 of them.
Know any good books about chelation therapy? Have an opinion on it as a preventative?
In Reply to: chelation posted by phil on February 19, 1998 at 00:23:10:
Try the new edition of Elmer Cranton, MD's classic: "Bypassing Bypass".
Then call the (800) in the back of his book (or in mine) for ACAM ) American College for the Advancement of Medicine)--the accrediting agency for Chelating Physicians.
They can give you more information than you probably want--PLUS the names of the closest certified chelating physicians.
See my note about chelation on my homepage for my personal & professional experience.