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LGS- wow!! A Medical Journal search. RESOURCES

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LGS- wow!! A Medical Journal search.

Posted by
Anthony on August 28, 2003 at 01:02:57:

For those of you interested,

I spent a couple hours going through articles with PubMed, mostly from Medical Journals, and was very surprised to find plenty of evidence and research to support the concept of Leaky Gut Syndrome.

There were several articles supporting the link between allergies initiating increased gut permeability and potentiating it.
Antigen handling by the small intestine., Clin Gastroenterol. 1986 Jan;15(1):1-20.
Dietary antigens: uptake and humoral immunity in man., APMIS Suppl. 1988;1:1-40.
Antigen absorption by the jejunal epithelium of children with cow's milk allergy., Pediatr Res. 1988 Aug;24(2):197-202.

Additionally there is a study published in "Gastroenterology" with mice that showed how chronic stress can result in increased gut permeability.
Chronic stress induces mast cell-dependent bacterial adherence and initiates mucosal inflammation in rat intestine., Gastroenterology. 2002 Oct;123(4):1099-108.

There were also some other articles showed that certain conditions (e.g. atopic eczema and potentially others) maybe a result of increased gut permeability (i.e. allowing excess unwanted antigens into the bloodstream).
Increased intestinal permeability in atopic eczema., J Invest Dermatol. 1986 Feb;86(2):101-4.
Food allergy in migraine. Study of dietary exclusion and RAST., Lancet. 1980 Jul 5;2(8184):1-4.

Another article stated, "alteration of the gut flora, impaired host immune defenses, or direct gut mucosal injury may result in gut barrier failure."
Nutritional support of the gut: how and why., New Horiz. 1994 May;2(2):193-201.

One article also mentioned that NSAIDS (Nonsteroidal Anti-inflammatory Drugs) and oxidant stress among other things can disrupt the gut barrier.
Intestinal Permeation and Gastrointestinal Disease ,JOURNAL OF CLINICAL GASTROENTEROLOGY 2002;34:385-396.

These were found as I said doing a search with PubMed. The words I used for the searches included "Increased Gut Permeability", "Increased Gut Permeability and Stress" and "Increased Gut Permeability and Food Allergies". I'm not too sure of how to include in text links. Sorry those who don't have time or are too lazy.

Here is the website to search PubMed: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi.

Hope this satisfies the skeptical ones and helps others

Anthony





Real good

Posted by jen on August 28, 2003 at 01:18:24:

In Reply to: LGS- wow!! A Medical Journal search. posted by Anthony on August 28, 2003 at 01:02:57:


But, as usual, they get it a little backwards.

Allergies do not cause Leaky Gut. Leaky Gut causes allergies.

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Re: LGS- wow!! A Medical Journal search. (Archive in LGS.)

Posted by Walt Stoll on August 29, 2003 at 12:26:25:

In Reply to: LGS- wow!! A Medical Journal search. posted by Anthony on August 28, 2003 at 01:02:57:

Thanks, Anthony.

Reminds me of the famous quote by Benjamin Frankin: "You will observe with concern how long a useful truth may be known and exist before it is generally received and practiced on."

Once the conventional docs stop denying that it exists, they will figure out that they have the cart before the horse (thanks Jen). Great thinkers have been figuring this out for nearly 20 years. The arrogance of the conventional medical mind thinks complete understand will burst upon them instantaneously with little effort.

Walt

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