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Hey Walt - a leaky gut connection

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Hey Walt - a leaky gut connection

Posted by Tom [11484.7906] on March 24, 2011 at 22:36:45:

ScienceDaily (Mar. 23, 2011) — A lot of chatter goes on inside
each one of us and not all of it happens between our ears.
Researchers at McMaster University discovered that the "cross-
talk" between bacteria in our gut and our brain plays an
important role in the development of psychiatric illness,
intestinal diseases and probably other health problems as well
including obesity.
See Also:
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"The wave of the future is full of opportunity as we think about
how microbiota or bacteria influence the brain and how the bi-
directional communication of the body and the brain influence
metabolic disorders, such as obesity and diabetes," says Jane
Foster, associate professor in the Department of Psychiatry
and Behavioural Neurosciences of the Michael G. DeGroote
School of Medicine.
Using germ-free mice, Foster's research shows gut bacteria
influences how the brain is wired for learning and memory. The
research paper has been published in the March issue of the
science journal Neurogastroenterology and Motility.
The study's results show that genes linked to learning and
memory are altered in germ-free mice and, in particular, they
are altered in one of the key brain regions for learning and
memory -- the hippocampus.
"The take-home message is that gut bacteria influences
anxiety-like behavior through alterations in the way the brain is
wired," said Foster.
Foster's laboratory is located in the Brain-Body Institute, a joint
research initiative of McMaster University and St. Joseph's
Healthcare in Hamilton. The institute was created to advance
understanding of the relationship between the brain, nervous
system and bodily disorders.
"We have a hypothesis in my lab that the state of your immune
system and your gut bacteria -- which are in constant
communication -- influences your personality," Foster said.
She said psychiatrists, in particular, are interested in her
research because of the problems of side effects with current
drug therapy.
"The idea behind this research is to see if it's possible to
develop new therapies which could target the body, free of
complications related to getting into the brain," Foster said.
"We need novel targets that take a different approach than
what is currently on the market for psychiatric illness. Those
targets could be the immune system, your gut function…we
could even use the body to screen patients to say what drugs
might work better in their brain."


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Re: Hey Walt - a leaky gut connection--archive

Posted by Walt Stoll [93.9196] on March 25, 2011 at 05:58:49:

In Reply to: Hey Walt - a leaky gut connection posted by Tom [11484.7906] on March 24, 2011 at 22:36:45:

Amen, Tom!

I am glad to see that many other professionals are getting on the "band wagon" about this. We have been promoting this idea on this website for years.

Walt


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Re: Hey Walt - a leaky gut connection

Posted by k. [884.9224] on March 25, 2011 at 14:53:42:

In Reply to: Hey Walt - a leaky gut connection posted by Tom [11484.7906] on March 24, 2011 at 22:36:45:

Thanks Tom, very interesting!


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Re: Hey Walt - a leaky gut connection

Posted by AT [11797.9523] on March 25, 2011 at 15:54:22:

In Reply to: Hey Walt - a leaky gut connection posted by Tom [11484.7906] on March 24, 2011 at 22:36:45:

What do they mean by germ free mice?


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