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Dr. Stoll-
I've read some of your archives about MCS, and it seems that the cause is usually LGS/Candida.
My mother has the signs of MCS as she is allergic/sensitive to many perfumes and chemicals, even wool, however....she has NO stomach symptoms. She has never even experienced constipation or diarrhea in her life (ever), has no bloating or pain, and is as regular as rain. These allergies cause major thick throat drainage and sinus headaches....evenually sinus infections sometimes.
Should wants to practice wellness in her life, but should she go so far as to assume she has and treat LGS/Candida even though she has no direct stomach symptoms?
Thank you-
DJ
In Reply to: MCS posted by DJ on March 15, 2002 at 09:47:35:
Hi, Dj.
In MY experience whether one has GI symptoms with LGS or Candida is a matter of their genetic makeup and not a matter of what they have. One person with LGS & Candida will present with arthritis, another with MCS, another with asthma or allergies, another with skin problems, another with GI symptoms, etc. The causes are all the same but the body's response is different in each individual.
Hope this helps.
Since the tests are mostly not available to determine this, at present the quickest and most accurate way to figure it out is to vigorously deal with the LGS and ? Candida and see what happens to the person's symptoms after the delay needed for which condition is going on. For example, if it is GI symptoms, only a few weeks of months. With MCS, at least 6-12 months, etc.
Walt
In Reply to: Re: MCS (Archive in LGS.) Multible possibilities based upon genetics. posted by Walt Stoll on March 16, 2002 at 10:08:35:
Dr. Stoll-
Thank you. That really does help me to understand the issue, and makes it clear that she needs to deal with LGS/Candida in spite of her lack of stomach symptoms in order to get to the MCS and allergies. (I guess the actual term "Leaky GUT" was throwing me off!)
She also has A LOT of mercury in her mouth, and has had a lot of dental work over the years. I know that mercury is a a bad thing and can cause lots of problems, but if she's treating her problems through the wellness program, can she avoid having to have the mercury removed? Or is it necessary to have it removed in ANY circumstance?
Thanks-
DJ
In Reply to: Re: MCS (Archive in LGS.) Multible possibilities based upon genetics. posted by DJ on March 16, 2002 at 10:52:42:
Thanks, DJ.
I may get into trouble with MAI for this but here goes:
It is documented that 10% of the population is hypersensitive to mercury traces and it is they who have all these horrendous problems.
HOWEVER, even those above the 10% line on the Bell Curve, have subclinical problems with mercury. It is now accepted by nearly everyone that the slightest traces of lead cause measurable brain damage. The only acceptable level in the human is ZERO.
The same thing is true of radiation. There are no safe levels.
I predict that the same will be found to be true of mercury. It is already known that it serves no useful purpose in the bodymind and is an enzymatic poison.
Since the tests for hypersensitivity to mercury are in their infancy, many people who do not test hypersensitive do have clinical conditions that would clear up if they got rid of at least some of their body burden of mercury.
SO, removiong mercury from her system might help, There is no real way to KNOW. However, you might have her tested by a holistic and knowledgable dentist, for hypersensitivity. If she tested positive, I would certainly have the mercury dealt with. If not, I would do the other things and see if she still had any symptoms.
Walt
In Reply to: Re: MCS (Archive in mercury.) Multible possibilities based upon genetics. posted by Walt Stoll on March 17, 2002 at 09:20:45:
Dr. Stoll - No you will NOT get in trouble with me.
The issue of mercury poisoning is VERY difficult as there is NO way to determine when mercury ia "acting" on.
The problem is that as you've stated that 10% of the population KNOWS that is hypersensitive to mercury traces and it is they who have all these horrendous problems.
Until now no one ever made registry of mercury poisoning victims.
Since there is a GAG and doctors are prohibited to talk about mercury the effects of nercury poisoning are severly underestimated as far as percentage.
Should they only know the percentage will go easily over 40% instantly ...
So as you've noticed it is 10% only because those who know are able to report the causation ...
At the same time the diagnosis of MCS is vigorously fought by QUACKS ...
Allergic Mercury Reaction in Genetic Subset (I personaly do not belive in GENETIC Predisposition - rather secondary damage from THIMEROSAL!)
Introduction.
Human allergy to Hg has been recognized for a long time and although the specific genetic code is not worked out, this allergy is strongly suspected to be of genetic origin.
It is estimated to affect between 2 and 5% of the human population (247,248). The North American contact hypersensitivity to Hg is reportedly 5.4% (249). Predisposition to mercury allergy has recently been investigated in genetically selected rodents.
Interestingly, special rodent strains develop significant
immune aberrations and autoimmune disease in Hg exposure, including exposure by implanted dental amalgam Hg configured as in human exposure (250,251).
In humans carrying dental amalgams, the amounts of Hg released have been estimated within the range that would cause reactions in those genetically susceptible to Hg (251). Therefore the millions of humans who carry Hg amalgams are theoretically at risk for genetically induced reactions. (Whether those not genetically susceptible could also be directly toxically affected by mercury is unknown; many widely divergent opinions and research reports have been published over the last few decades (247,248,251-256).
Recent reports connect amalgams with oral cavity ill-health (248,257), increase in antibiotic-resistant bacteria in oral and intestinal cavities (258), multiple sclerosis (259,260), psychological complaints such as depression, excessive anger, and anxiety (261), and cardiovascular symptoms such as fatigue and high blood pressure (262).
Mercury is also available in the diet, particularly from fish. Levels of methyl mercury (MeHg) in fish appear to be growing and are a concern (263,264). An epidemiologic investigation of a fish-eating population is reported to show high susceptibility to brain damage during prenatal exposures to MeHg (263). Also Hg in paint is a widely recognized health hazard (265-267), as is skin-lightening cream (268).
A syndrome of infant Hg toxicity called acrodynia is reported from application of calomel teething powders (255) and from paint exposures (267). A case-control study shows increased urinary Hg in people living in houses painted with Hg-latex paint (p<0.001) (267), and a case of acrodynia occurred in a child living in such a house (267).
Before 1990 one-third of the interior latex paint used in the United States had added Hg fungicide (267).
Like MeHg, Hg is toxic to the CNS and established detrimental effects range from behavioral irritability and insomnia at low levels of exposure through tremors, muscle spasms, and nerve conduction loss at higher exposure levels (253). Many other toxic effects are reported (255), including cardiovascular (262), immune (248,255), and autoimmune effects (269).
Data on a direct connection of Hg exposure to MCS is lacking except for the synchronicity of neurologic symptoms, which are the most highly reported symptom category in MCS clinical literature and the symptoms most commonly produced by Hg. These reasons and the demographics prompted this exploratory model. Half the population of the western world has Hg amalgam fillings, and 5% may be allergic to Hg.
Initial Damage.
We hypothesize a human strain that has a genetically determined immune response to Hg and a subject who has sufficient dental Hg released in the body to induce a systemic autoimmune reaction through the IRA. Subsequent to this the Hg level in the subject's body is being increased by food sources, further increasing the activity of the autoimmune response. Then a moderate-to-high exposure to toxic environmental Hg in paint, drugs, pesticides, cosmetics, or other source occurs during a stressful situation that includes a chemical exposure. For example Hg in fresh paint, in cosmetics or calomel, or in amalgam implantation in a dentist's office in conjunction with anesthetic injection or ambient chemicals might provide this combination. This exposure causes SR activation, and in combination with the ongoing autoimmunity, a combined CNS-mediated TDS to Hg and to the stress-associated chemical may begin. Because there is already an appreciable body burden of Hg and also an immune response to this Hg, there may be a messenger crossover--ACTH, ß-endorphin, IL-1, or other immune cells or messengers, for example--between the TDS and the immune and SRs. This may change the threshold of response of any of these IDSs. This combined sensitization of the immune response and TDS to internal Hg may create an unstable situation that allows subsequent exposures to become conditioned inciters of the TDS during various situations; e.g., those that elicit movement or increase of the Hg body burden while stressing psychologically or chemically.
Extensions.
HEAVY METALS/ZINC DISPLACEMENT.
Cd, Pb, and Hg are all Zn agonists, and rising levels of Cd and Pb can add to the toxic effect of Hg in the body. Metals are unique in the environment in that they are not consumed by human enterprise and so continue to increase in the biosphere as we collect and process them (270); one review concludes that we have a growing problem of heavy metal toxicity (270). Cd is increasing in human tissue. It has a human half-life of 30 years (271) and the average human body burden since the turn of the century has increased by a factor of 4.7 according to one study (272), with the renal concentration increasing by a factor of 47 (272). Another study found a renal increase factor of 3.8 (273). Cd is a potent developmental toxin in animal studies; its effects include CNS and behavioral dysfunctions and many others (274). Some Cd effects have been linked to its displacement of Zn from various enzymes (270,274), and Cd from maternal smoking is thought to decrease the transfer of Zn across the human placenta (275,276), which may implicate Cd in multiple teratogenic effects strongly suspected to result from Zn gestational deficiency (44,193). Pb caused a reduction in cognitive development through 7 years of age in children living in a lead-smelting community (277). Pb is also reported to cause DNA-protein crosslinks and DNA repair inhibition (270), and to accumulate in the hippocampus of children, rats, and monkeys. In monkeys the effects are accompanied by Zn displacement and learning deficits (278).
CHILDHOOD OR GESTATIONAL MERCURY EXPOSURES.
MeHg exposure during pregnancy causes neurologic abnormalities, including psychomotor deficits, mental retardation, and deafness in children (279). Fetal effects occur at much lower exposure levels than required for effects in adults, although in both cases effects are almost exclusively on the nervous system, especially the CNS (268). Hg is not known to damage the fetus as heavily as MeHg, but this may be because of lack of study (253).
FOR FULL ARTICLE: CLICK ON the LINK.
In Reply to: Re: MCS (Archive in mercury.) Multible possibilities based upon genetics. posted by MAI on March 19, 2002 at 16:48:42:
Thanks, MAI.
I agree that the hypersensitivity % may be grossly underestimated.
However, the study I saw was from ostensibly healthy people, not from dentist files.
The hooker was that they were only testing for conventional allergy which is serum allergy, Since it is known that the vast majority of hypersensitivity problems are NOT serum based...........
Namaste`
Walt
In Reply to: Re: MCS (Archive in mercury.) Multible possibilities based upon genetics. posted by Walt Stoll on March 20, 2002 at 09:43:58:
"....the study I saw was from ostensibly healthy people, not from dentist files....
The hooker was that they were only testing for conventional allergy which is serum allergy, Since it is known that the vast majority of hypersensitivity problems are NOT serum based ...."
Well said!
That is IDIOCRACY of the improper testing performed for strange reasons other than patient real needs.
What allways puzzled me is if they KNOW what they are doing or they just follow the standard of care dictated by their Labor Union (AMA, AAAAAI) !
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