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First the good news: I went on an elimination diet and found that my stomach felt much better on a diet of fish and turkey and vegetables.
Now the bad news: I have mercury and arsenic poisoning. On the mercury hair test I was 6.2 with a reference range of <1.1. RBC minerals test showed mercury .0446 with an expected range of < .01. My doctor wants to do a provocative 24 hr urine test with DMSA 100mg 3 times a day for seven days. This dosage seems high to me since Dr. Huggins recommends treatment doses of 25-50mg per day. I can't find much info on this since most sites deal with amalgamum issues, not food poisoning. I have only one mercury filling that is at least 10 years old.
In Reply to: I need info on DMSA. posted by Dawn G. on August 03, 1999 at 10:27:34:
Before you go on DMSA get your mercury filling out!
Read about DMSA:
http://www.teleport.com/~ctseng/cfs_pages/chelation.html
Mercury poisoning from food? that is a joke!
Unless you had bad water, it is from other sources.
It was recently confirmed that some bacteria produces mercury methyl!.
There is NO FOOD that could cause mercury poisoning!
The story about mercury from the fish, it is a horse manure!
You will have to eat 5 tons of fish a week to get poisoning.
Most likely it is from fungicides or pesticides.
There is however now a very common strange wave of people who are now coming with mercury poisoning, while have not consumed food with alleged sources of mercury.
The typical signs and symptoms of mercury poisoning are metalic taste, sores in the mouth, swollen salivary glands under tongue, carpal tunel, chronic fatigue and asthma.
You could have more likely some occupational poisoning by mercury. It is unlikely from other sources.
In agricultural regions poisoning by mercury from fungicides and pesticides is more common (check water source for mercury).
Please note that carpal tunel is caused by dental amalgam poisoning and not by computer keyboards. Unfortunatelly the surgents do not know to much about neurotoxicity.
BE SURE TO FILE COMPLAI WITH FDA. It is more likely than not, that even the single mercury filing could cause such poisoning!
Study DMSA about amalgams that is the same!
Doses of DMSA shall be proportional to your weight.
Go on the INTERNET and look at mercury amalgam.
Siblerud, R.L. "Health Effects After Dental Amalgam Removal" Journal of Orthomolecular
Medicine. Vol. 5, No. 2, (1990).
SUMMARY: A Utah dentist provided the names and addresses of approximately 300 people who had
their amalgams removed. A health questionnaire was sent to these people; 86 subjects responded.
Eighty (80) % of the subjects reported that they felt better following amalgam removal. Nearly all of the
subjects 91% said they were glad their amalgams had been removed and 88% said they would do it
again. An increase in happiness and peace of mind was experienced by 58% of the subjects. This
evidence suggests that the well being of these subjects improved immensely after amalgam removal.
Mary Davis editor "Defense Against Mystery Syndromes" Chek Printing Co. March 1994
SUMMARY: This book presents patient reported case histories, where they associate their health
problems to dental amalgam mercury. Case histories include: Chronic Fatigue Syndrome, Seizures,
Memory Loss, Migraines, Multiple Allergies, Multiple Sclerosis, Depression, Lupus, Maldigestion,
Chemical Sensitivities, Insomnia, Miscarriages, Paralysis, Sinus Problems, Emotional & Mental Disorders,
Infertility, Endometriosis, Crohn's Disease, Rashes, Anxiety, Tremors & Spasms, Amyotrophic Lateral
Sclerosis, Universal Reactor and many others.......
http://www.amalgam.org/#anchor69176
http://www.unpronounceable.com/amalgam/index.html
In Reply to: I need info on DMSA. posted by Dawn G. on August 03, 1999 at 10:27:34:
methyl mercury and Microorganisms
There are gaps in the science literature regarding how the human body derives methyl
mercury from inorganic dental mercury.
After much searching, I've come up with no references that would indicate human metabolic
processes perform this mercury transformation. One does find that methyl cobalamin
(methyl B12) will spontaneously react with inorganic mercury creating a methyl mercury
compound. This reaction occurs just by having the two molecules in solution in a petri dish.
Plenty of evidence exists to show human demethylization and the creation of mercury
proteins. There is data to show mercury binding into all kinds of human molecular structures
causing disruption.
Metabolic conversion to free form methyl mercury by humans or mammals cannot be
substantiated in the literature. One reference I found, and included on another page,
addresses this explicitly.
So how does the mercury get to be methyl mercury in the human starting from dental
amalgam ? Dental amalgam irrefutably contains only inorganic mercury. Another agent must
be at work. Microorganisms in the mouth and GI track gut quickly come under suspicion.
Behold, the gut does contain micro flora with this capability. Yeast, strep, staff and E. coli all
perform the transformation, it's referenced here, it's proven.
Strep and staff are 100% pathogenic. Your health has near zero tolerance for these
organisms, though they often maintain a limited presence outside the cell linings of the gut.
It is very unlikely these pathogens contribute to a long term mercury conversion process.
Infections of these organisms are generally acute in nature.
Yeast and E. coli are the two most compelling organisms to suspect since both are usually
not pathogenic, often behave symbiotically, and are known to live in most guts.The ability to
transform dental mercury to methyl mercury is already living within the mouth and GI track
of everyone who has a mercury dental filling.
Read on for medical and scientific journal references that substantiate this point.
"Transformations of inorganic mercury by Candida albicans and Saccharomyces
cerevisiae"; Applied and Environmental Microbiology, Jan 1991; 57:1:245-247; S Yannai; I
Berdicevsky, L Duek; Dept. of Food Engineering and biotechnology, and Unit of Microbiology,
Faculty of Medicine, Technion-Israel Institute of Technology
"Saccharomyces cerevisiae and Candida albicans were incubated with 0.25, 0.5, or 0.75 ug of
Hg (as HgCl2) per ml of Nelson's medium in the presence of trace amounts of oxygen at 28
°C for 12 days. Two controlled media were used, one without add Hg and one with out yeast
inoculum. Yeast cell growth was estimated after 1, 2, 3, and 8 days of incubation. The
contents of organomercury in the system and of elemental mercury released from the media
and collected in traps were determined at the end of the experiments. The results were as
follows. (i) C. albicans was the more mercury-resistant species, but both yeast species failed
to grow in the media containing 0.75 ug per ml. (ii) (iii) The amounts of organomercury
produced by the two species were proportional to the amount of HgCl2 added to the
medium. In all cases C. albicans produced considerably larger amounts of elemental Hg
produced were all similar in the case of C. albicans. (iv) Neither organomercury nor
elemental Hg was produced in any of the control media."
Experiment and Findings
1. Anerobic fermentation process, closed system with outlet only.
2. 14 day fermentation period.
2. Culture flask and fermentation effluent traps.
3. In the Candida albicans flasks, 0.9%-1% of the original mercury/ml was free as
organomercury.
4. In the traps 9-10% of the original mercury/ml was free as organomercury.
5. There was not a full accounting of original mercury: how much in yeast ? how much still in
original species ?
6. Authors believe the organomercury was methyl mercury, they are certain it was a carbon
bearing compound.
"Speciation of methyl mercury and Hg(II) using bakers yeast biomass
(Saccharomyces cerevisiae) determination by continuous flow mercury cold vapor
generation atomic absorption spectrometry"; Anal. Chem.; 1995; 67:750-754; Y
Madrid, Ca Cabrera, T Perez-Corona, C Camara; Departmento de Quimica analitica, Facultad
de Quimicas, Universidad Complutense, 28040 Madrid, Spain.
"Bakers yeast cells (Saccharomyces cerevisiae) were successfully used to selectively separate
methyl mercury and Hg(II). Several parameters affecting the degree of biosorption and the
binding kinetics of methyl mercury and Hg(II) were evaluated: solution pH;
temperature,incubation time, amount of biomass and analyte, and presence of foreign ions.
methyl mercury is immediately bound to the yeast cells over a wide pH and temperature
range. The fraction of methyl mercury bound was in all cases 100% and was unaffected by
the parameters mentioned above. Hg(II) has less affinity for yeast cells and remains in
solution, although the percentage of Hg(II) bound to the cell mass does increase at high
incubation time (3 hours) and biomass. Of the foreign ions tested, chloride at high
concentrations strongly increases the Hg(II) binding efficiency. methyl mercury and Hg(II) are
quantitatively separated under optimum conditions, i.e. 30 minutes incubation time at pH
7.0 and 37 °C. The results were compared with those obtained using a S. cerevisiae isolate,
and no significant differences were observed. Our work suggests that the cell rapidly
reduces CH3Hg+ to more volatile species such as Hg(I) or Hg0, whereas Hg2+ is slowly
bound and reduced, perhaps because of the different toxicities of the two species. The
method was applied to the selective determination of Ch3Hg+ and Hg(II) spiked water
samples. In all cases good recoveries were obtained."
"The cell membrane is one of the major barriers along the toxicological pathways of
hazardous substances. Consequently, living cell systems can be used as an analytical tool for
trace analysis.
Various microorganisms are capable of binding dissolved metals in a variety of
environments. Microbes, composed mainly of polysaccharides, proteins, and lipids, offer
particularly abundant metal-binding functional groups. Other biological processes that can
occur include methylization, demthylization, and reduction. These properties can be used
not only for removing heavy metal ions from polluted environments but also for
differentiating species according to their toxicity. although living organisms have been
widely used to preconcentrate metal ions, there have been few attempts to apply this kind
of substrate to metal speciation. Neidhart et al. used human red blood cells for specific
sampling of chromate even at high levels of Cr(III).
Mercury is a toxic metal whose toxicity depends on its chemical form. methyl mercury is
more toxic tha Hg2+, not only for humans but also for microorganisms. Microorganisms
(bacterias, yeasts, and other fungi) mediate three transformations of mercury: they reduce
Hg(II) to Hg0, they break down methyl mercury (and other organomercury compounds), and
they methylate Hg(II). Hg(II) is also reduced and methylated by chemical reactions in the
environment other than those mediated by microorganism. This paper discusses the
potential of the yeast cell for the speciation of methyl mercury and Hg(II). The effects of Ph,
temperature, incubation time, mercury and yeast concentration, and interferences from
other metals are examined."
"Sub-cellular Location of Mercury in Yeast Grown in the Presence of Mercuric
Chloride"; Journal of General Microbiology; 1975; 86:66-74; AD Murray; DK Kidby; Dept. of
Microbiology, College of Biological Science, University of Guelph, Guelph, Ontario, Canada.
"The distribution of 203Hg in Saccharomyces cerevisiae grown in the presence of mercuric
chloride has been examined by physical and chemical fractionation procedures and
autoradiography. The major fraction of the bound mercury is tightly bound to the wall. A
significant quantity of mercury penetrates to the cytoplasm but only a minor fraction is
present as low molecular weight compounds. The wall associated mercury is not readily
released by extraction with sodium hydroxide or ethylenediamine but a major fraction is
solubilized by Pronase and Helicase treatment. Isolated walls are capable of binding their
own weight of mercury to high affinity adsorption sites. The major role of the cell envelope
in the in vivo binding of mercury and the penetration to the cytoplasm of mercury was
confirmed by autoradiography."
"Growth of yeasts is inhibited by most heavy metals which have been examined (White &
Munns, 1951). Of the group comprising cadmium, lead and mercury, the last has been
extensively characterized as an inhibitor of enzymes due to it's number of functional groups
(Vallee & Ulmer, 1972). The extracellular B-glucosidase and B-fructosidase of yeast have
been shown to be extremely sensitive to mercury (Mealor & Townshend, 1968; Kaplan &
Tacreiter, 1966). However, despite the well documented phenomenom of mercury inhibition
of yeast, at both the moleular and cell level, there has been no investigation of the
distribution of mercury within the cell. We attempted to define the distribution of mercury
within the cell. We attempted to define the distribution of mercury in growing yeasts and to
indicate the general nature of the mercury binding sites."
Experiment and Findings
1. aerobic vs anaerobic conditions not specified, growth medium was liquid.
2. Incubation time was 15 hours.
3. Nearly all the mercury present was in the yeast cells, with almost none left in growth
medium.
4. Major fraction of mercury was bound into the cell walls, only a small proportion of this
appeared to be in weakly bound ion exchange positions.
5. Yeast walls are capable of binding approximately their own weight of mercury.
"The methylization of mercuric chloride by human intestinal bacteria"; Experentia,
31:9; 1975; Sept 15, 1064-5; IR Rowland; P Grasso; MJ Davies; British Industrial Biological
Research Association, Woodmansterne Road, Cashalton, Surrey, SM5 4DS, England.
"Most strains of staphylococci, steptococci, yeasts and E. coli isolated from human feces,
could synthesize methyl mercury compounds. In contrast, few strains of obligate anerobes
could do so. Up to 6 ng methyl mercury/ml were formed in 44 hours from 2 ug / ml
mercuric chloride."
Experiment and Findings
1. Except for lactobacillus and bifido-bacteria, all cultures incubated in aerobic conditions.
2. Streptococci had highest methylization rate, followed by Staph, and E. coli, then yeast.
3. Very few strains of GI friendly bacteria methylized. Those that did, produced extremely
little.
"Tissue content of mercury in rats given methylmeruric chloride orally: influence
of intestinal flora."; Arch Environ Health; 35:3, 1980 May-June; 155-60; IR Rowland; MJ
Davies; JG Evans; British Industrial Biological Research Association, Woodmansterne Road,
Cashalton, Surrey, SM5 4DS, England.
"The effect of intestinal flora on the absorption and disposition of mercury in tissues was
investigated using conventional rats and rats treated with antibiotics to eliminate their gut
flora.
Antibiotic treated rats given 203Hg labeled methylmercuric chloride orally had significantly
more mercury in their tissues, especially in kidney, brain, lung, blood, and skeletal muscle,
and also excreted less mercury in the feces than conventional rats. Furthermore, in the
kidneys of the antibiotic treated rats, the proportion of mercury present as organic mercury
was greater than in the kidneys of the conventional rats. The results support the hypothesis
that the metabolism of methylmercuric chloride by the gut flora reduces the tissue content
of mercury. When rats were administered 10 mg methylmercuric chloride/kg per day for 6
days, four of five of those given antibiotics developed neurological symptoms of toxicity,
whereas only only one of five conventional rats given methylmercuric chloride was affected."
Facts and Findings
1. Inorganic Hg compounds are absorbed very slowly in the mammalian intestine tract.
2. Alkyl-mercurial (carbon bearing mercury ) compounds are rapidly and completely
absorbed from the GI.
3. Rat feces were found to be free of bacteria after 3 days of the antibiotic regime.
4. After 30 days four of five rates given antibiotic treatment developed signs of severe
methyl mercury chloride (CH3HgCl) poisoning.
5. Only 1 of five conventional rates developed severe CH3HgCl poisoning in the same
period.
6. Intestinal microflora reduce the severity of damage to the granular layer of the
cerebellum
7. Intestinal flora play a protective role by effectively reducing the toxicity of ingested
CH3HgCl.
"Microbial transformations of metals"; Annu Rev Microbiol, 32:1978, 637-72; AO
Summers; Dept. of Microbiology, University of Georgia, Athens, GA 30602
"Biological Methylation of Mercury...
Three alternative pathways for mercury metabolism have been proposed. (a) bacteria living
in bottom sediment and sludge can carry out mercury methylation by excreting
methylcobalamin, which serves as a methyl donor in vitro. Indeed, bottom dwelling bacteria,
soil anerobes, and yeasts, have been shown to have the ability to methylate mercury....
(b) Second the mercury may be methylated by the normal bacterial flora of the gills and guts
of the fish...
(c) The third alternative for methyl mercury production is totally abiotic, without the
intervention of microbes or microbial metabolites..."
"Formation of methyl mercury by bacteria"; Appl Microbiol; 30:3, 1975; Sept; 424-32;
MK Hamdy; OR Noyes; Dept. of Food Science, University of Georgia, Athens, GA 30602.
"Twenty three Hg2+ resistant cultures were isolated from sediment of the Savannah River in
Georgia; of these, 14 were gram-negative shirt rods belonging to the Genera Escherichia
and Enterobacter, six were gram positive cocci (three Staphylococcus sp. and three
Streptococcus sp.) and three were bacillus sp. All the Escherichia, Enterobacter, and the
bacillus strain were more resistant to Hg2+ that the strains of staphylococci and
streptococci. Adaptation using serial dilutions and concentration gradient agar plate
techniques showed that it was possible to select a Hg2+ resistant strain from a parent
culture identified as enterobacter aerogenes. this culture resisted 1,200 ug of Hg2+ per ml
of medium and produced methylmercury from HgCl2, but was unable to convert Hg2+ to
volatile elemental mercury (Hg0). Under constant aeration (i.e., submerged culture), slightly
more methylmercury was formed than in the absence of aeration. Production of
methylmercury was cyclic in nature and slightly decreased if DL-homocysteine was present
in the media, but increased with methylcobalamine. Is is concluded that the bacterial
production of methyl mercury may be a means of resistance and detoxification against
mercurial in which inorganic Hg2+ is converted to organic form and secreted into the
environment."
"Effect of DL-homocysteine. Homocysteine was added in equimolar amounts to that of Hg2+
(0.25 umol of Hg2+ per ml of media) present in GBSB and the medium was then incubated
aerobically. The results showed the absence of MM, as detected by TLC or GLC, in the
benzene extract of control medium. It was also noted that the formation in the culture
media after 3 and 20 days of incubation"
"Biotoxicity of Mercury as Influenced by Mercury(II) Speciation"; Applied and
Environmental Microbiology, Oct. 1990, p. 3006-3016; RE Farrell; JJ Germida; PM Huang;
Department of Soil Science, University of Saskatchewan.
"Additions of cysteine at cysteine:Hg molar ratios greater than 1:10 to the M-IIY medium
produced significant (P=0.01) increases in the IC50 to the extent that Hg toxicity was
virtually eliminated at a cysteine:Hg molar ratio of 2:1."
In Reply to: I need info where from mercury came first! posted by JERRY on August 04, 1999 at 06:04:32:
Thanks, Jerry!
Walt
In Reply to: Re: I need info on DMSA. posted by JERRY on August 04, 1999 at 05:32:08:
Wonderful stuff, Jerry!
You have enriched our archives on the mercury problem!
Walt
In Reply to: Re: I need info on DMSA. (Archive) posted by Walt Stoll on August 05, 1999 at 13:09:55:
My personal study revealed that 85% of all illnesses are caused by mercury poisoning!
Should we eliminate mercury doctors and dentist will be homeless!
One of most shocking is carpal tunel always confused with egronomics of computers!
It is hard to believe in lack of intellectual capacity of many doctors. I do not want to hear such horse manure!
It is all mercury!
In Reply to: I need info on DMSA. posted by Dawn G. on August 03, 1999 at 10:27:34:
DMSA has been recommended for my 5 year old environmentally
autistic son. Someone please tell me if they have heard of
this? or had it done? Is it worth it. This is suppose to
help my son's autistic behaviors. Does it work?
Please help me. I need answers before wednesday 11/10/99
Thanks
In Reply to: Re: I need info on DMSA. posted by Cheryl on November 04, 1999 at 21:33:42:
There is not a huge amount of information on this site on DMSA, assuming you mean the DMSA that is an oral chelating agent.
I have placed a link below to a site that Walt has recommended in the past relating to dental mercury and chelation techniques and alternatives.
In Reply to: Re: I need info on DMSA. posted by Cheryl on November 04, 1999 at 21:33:42:
Hi, Cheryl.
If I had a child with autism, the first thing I would be doing is getting rid of his LGS and C-RS. This has been discussed on this BB for years and there are testimonials of success with this approach on this BB (Besides my professional experience for 20 years.)
See the glossary for any unfamiliar terms.
THEN, when you have more questions, write again.
Walt
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