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Hi Dr. Stoll,
I have a serious magnesium wasting disorder and am at wits end trying to figure out what is causing it.
The presenting symptom was suicidal depression. Since my very rapid recovery using magnesium glycinate, I have developed a strong interest in treating depression and hyperemotionality (ADHD, mania, bi-polar, anxiety, OCD, suicidal depression) with magnesium. I have created a large web page devoted to use of magnesium glycinate in treating depression and hyperemotionality generally at
http://george-eby-research.com . Many topics are covered.
I no longer have any depression problems or any health issues and am full of energy both mentally and physically.
Unfortunately, I am still wasting so much magnesium (by definition through kidneys) that I must take 200 mg of magnesium as glycinate every 4 hours to prevent cardiac palpitations (which are a reliable indicator of low magnesium in me). Is there hope for people like us that have no identifiable illness other than magnesium wasting? How can we restore our normal "non magnesium wasting" status so we will not need to be slaves to a bottle of magnesium?
I am also very sensitive to calcium and avoid it by eating no diary or calcium food supplements. In fact, once I elimninated calcium from my diet (calcium itself is a cause of depression), a single 500 mg calcium food supplement causes depression within an hour, and a 400 mg magnesium dose terminates that depression within an hour!
COMMENT: I notice that some people writing in your BB blame magnesium for their diarrhea. I feel certain that the diarrhea attendant with ingestions of large amounts of magnesium in the Western diets is much more likely due to injestion of high carbohydrate diets (which also cause intestinal problems resulting in impaired magnesium absorption) WITH magnesium than from magnesium ALONE, but magnesium gets the blame. Eliminating carbohydrates from the diet (going back to a more natural diet) eliminates the diarrhea blammed on magnesium and also terminates food cravings, with a 10 pound per month weight loss being achieved without any feeling that one is starving.
Any recommendations on terminating "magnesium wasting" though DRUG AND MEDICAL TREATMENT means would be appreciated. (I think I already have a SOLID handle on dietary means).
George Eby
In Reply to: Magnesium wasting, depression and cardiac palpitations posted by George Eby on June 23, 2003 at 13:05:19:
GREAT article! thanks for sharing that information:-)
In Reply to: Magnesium wasting, depression and cardiac palpitations posted by George Eby on June 23, 2003 at 13:05:19:
Thanks, George, for sharing this with the BB.
I would have to look it up, too. Ask your library to get you a copy of Mildred Seelig, MD's classic book on magnesium. Also, Jean Durlach's "Magnesium in Clinical Practice".
Let us know what you learn.
Walt
In Reply to: Magnesium wasting, depression and cardiac palpitations posted by George Eby on June 23, 2003 at 13:05:19:
Hi George,
It's strange that you have a problem with calcium, as it is supposed to go with magnesium. I also had a magnesium deficiency and control my dysarrithmia and leg and foot cramps with magnesium glycinate. I do not take calcium but have always wondered whether I should. I decided not to on the basis that I don't get much magnesium in my diet but Ido get calcium. It's a bit of trial and error with me.
I haven't read the article yet, but will do. Many thanks for posting.
I know nothing about magnesium wasting. Good luck. Hope some other board users can throw some light on it.
In Reply to: Magnesium wasting, depression and cardiac palpitations posted by George Eby on June 23, 2003 at 13:05:19:
Med Hypotheses. 1996 Feb;46(2):89-100.
Complementary vascular-protective actions of magnesium and taurine: a rationale for magnesium taurate.
McCarty MF.
Nutrition 21, San Diego, CA 92109, USA.
By a variety of mechanisms, magnesium functions both intracellularly and extracellularly to minimize the cytoplasmic free calcium level, [Ca2+]i. This may be the chief reason why correction of magnesium deficiency, or induction of hypermagnesemia by parenteral infusion, exerts antihypertensive, anti-atherosclerotic, anti-arrhythmic and antithrombotic effects. Although the amino acid taurine can increase systolic calcium transients in cardiac cells (and thus has positive inotropic activity), it has other actions which tend to reduce [Ca2+]i. Indeed, in animal or clinical studies, taurine lowers elevated blood pressure, retards cholesterol-induced atherogenesis, prevents arrhythmias and stabilizes platelets--effects parallel to those of magnesium. The complex magnesium taurate may thus have considerable potential as a vascular-protective nutritional supplement, and might also be administered parenterally, as an alternative to magnesium sulfate, in the treatment of acute myocardial infarction as well as of pre-eclampsia. The effects of magnesium taurate in diabetes deserve particular attention, since both magnesium and taurine may improve insulin sensitivity, and also may lessen risk for the micro- and macrovascular complications of diabetes.
In Reply to: Re: Magnesium wasting, depression and cardiac palpitations posted by George Eby on June 24, 2003 at 06:50:15:
It said on your site taurate was a neurotoxin and to avoid it
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